An overview of pharmaceutical intermediates industry.
Column:Industry Trends Time:2017-12-28
An overview of pharmaceutical intermediates industry.

The so-called pharmaceutical intermediates are the chemical raw materials or chemical products that the drugs need to be used in the synthesis process.Such chemical products can be produced in ordinary chemical plants without obtaining a drug production license. As long as the technical indicators meet certain level requirements, they can be used to participate in the synthesis and production of drugs.Although the synthesis of drugs belongs to the chemical industry, it is stricter than the general chemical products.Medicine and API manufacturers need to accept GMP certification, and manufacturer of intermediates are not necessary, because the intermediate product is the synthesis and production of chemical raw materials, in the pharmaceutical production chain is the most basic and at the bottom of the product, can't call drug, so there is no need to GMP certification, this also gives intermediates manufacturers to reduce barriers to entry in the industry.

Pharmaceutical intermediates can be divided into major categories, such as antibiotic drugs intermediates, antipyretic analgesics, medicinal intermediates, anticancer drug intermediates, etc.Specific pharmaceutical intermediates products is very much, such as imidazole, furan, phenolic intermediates, aromatic intermediates, pyrrole, pyridine, biochemical reagents, sulfur, nitrogen, halogen compounds, heterocyclic compounds, microcrystalline cellulose, starch, mannitol, lactose, dextrin, ethylene glycol, powdered sugar, inorganic salts, ethanol intermediates, stearic acid, amino acid and ethanol amine salt, sylvite, sodium salt and other intermediates and so on.

In addition, in recent years due to the drug regulatory requirements is more and more strict, pharmaceutical research difficulty increasing, rising prices such as background, the multinational pharmaceutical enterprises to shorten time to market, patent medicine research and development, production to reduce costs, in the whole life cycle of good profit space, to improve their management efficiency, gradually from the "vertical integration" business model to the "development and cooperation" business model transformation, the patent medicine research, development, production and other business link professional decomposition, and outsourcing to the medical contract research, medicine and custom research and development production enterprises, professional institutions, such as the medical custom research and development production (CMO).